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A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies
Antibody engineering technologies face increasing demands for speed, reliability and scale. We develop CeVICA, a cell-free nanobody engineering platform that uses ribosome display for in vitro selection of nanobodies from a library of 10(11) randomized sequences. We apply CeVICA to engineer nanobodi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448731/ https://www.ncbi.nlm.nih.gov/pubmed/34535642 http://dx.doi.org/10.1038/s41467-021-25777-z |