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A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies

Antibody engineering technologies face increasing demands for speed, reliability and scale. We develop CeVICA, a cell-free nanobody engineering platform that uses ribosome display for in vitro selection of nanobodies from a library of 10(11) randomized sequences. We apply CeVICA to engineer nanobodi...

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Detalles Bibliográficos
Autores principales:	Chen, Xun, Gentili, Matteo, Hacohen, Nir, Regev, Aviv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448731/ https://www.ncbi.nlm.nih.gov/pubmed/34535642 http://dx.doi.org/10.1038/s41467-021-25777-z

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