CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1

Transcriptional factor nuclear factor κB (NF-κB) can be activated by various intracellular or extracellular stimuli and its dysregulation leads to pathological conditions, such as neurodegenerative disorders, infection, and cancer. The carboxyl terminus of HSC70-interacting protein (CHIP), a pathoge...

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Detalles Bibliográficos
Autores principales: Liu, Yuchun, Sun, Yao, Han, Shaoming, Guo, Yanan, Tian, Qingnan, Ma, Qiang, Zhang, Shoutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448743/
https://www.ncbi.nlm.nih.gov/pubmed/34535633
http://dx.doi.org/10.1038/s41420-021-00637-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448743/
https://www.ncbi.nlm.nih.gov/pubmed/34535633
http://dx.doi.org/10.1038/s41420-021-00637-3

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