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CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1
Transcriptional factor nuclear factor κB (NF-κB) can be activated by various intracellular or extracellular stimuli and its dysregulation leads to pathological conditions, such as neurodegenerative disorders, infection, and cancer. The carboxyl terminus of HSC70-interacting protein (CHIP), a pathoge...
Autores principales: | Liu, Yuchun, Sun, Yao, Han, Shaoming, Guo, Yanan, Tian, Qingnan, Ma, Qiang, Zhang, Shoutao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448743/ https://www.ncbi.nlm.nih.gov/pubmed/34535633 http://dx.doi.org/10.1038/s41420-021-00637-3 |
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