Post-transcriptional screen of cancer amplified genes identifies ERBB2/Her2 signaling as AU-rich mRNA stability-promoting pathway

Amplification of specific cancer genes leads to their over-expression contributing to tumor growth, spread, and drug resistance. Little is known about the ability of these amplified oncogenes to augment the expression of cancer genes through post-transcriptional control. The AU-rich elements (ARE)-m...

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Detalles Bibliográficos
Autores principales: Al-Matouq, Jenan, Al-Haj, Latifa, Al-Saif, Maher, Khabar, Khalid S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448767/
https://www.ncbi.nlm.nih.gov/pubmed/34535639
http://dx.doi.org/10.1038/s41389-021-00351-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448767/
https://www.ncbi.nlm.nih.gov/pubmed/34535639
http://dx.doi.org/10.1038/s41389-021-00351-w

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