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Post-transcriptional screen of cancer amplified genes identifies ERBB2/Her2 signaling as AU-rich mRNA stability-promoting pathway
Amplification of specific cancer genes leads to their over-expression contributing to tumor growth, spread, and drug resistance. Little is known about the ability of these amplified oncogenes to augment the expression of cancer genes through post-transcriptional control. The AU-rich elements (ARE)-m...
Autores principales: | Al-Matouq, Jenan, Al-Haj, Latifa, Al-Saif, Maher, Khabar, Khalid S. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448767/ https://www.ncbi.nlm.nih.gov/pubmed/34535639 http://dx.doi.org/10.1038/s41389-021-00351-w |
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