METTL3-mediated m(6)A RNA methylation promotes the anti-tumour immunity of natural killer cells

Natural killer (NK) cells exert critical roles in anti-tumor immunity but how their functions are regulated by epitranscriptional modification (e.g., N(6)-methyladenosine (m(6)A) methylation) is unclear. Here we report decreased expression of the m(6)A “writer” METTL3 in tumor-infiltrating NK cells,...

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Detalles Bibliográficos
Autores principales: Song, Hao, Song, Jiaxi, Cheng, Ming, Zheng, Meijuan, Wang, Tian, Tian, Sha, Flavell, Richard A., Zhu, Shu, Li, Hua-Bing, Ding, Chen, Wei, Haiming, Sun, Rui, Peng, Hui, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448775/
https://www.ncbi.nlm.nih.gov/pubmed/34535671
http://dx.doi.org/10.1038/s41467-021-25803-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448775/
https://www.ncbi.nlm.nih.gov/pubmed/34535671
http://dx.doi.org/10.1038/s41467-021-25803-0

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