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Lung transplantation for idiopathic multicentric Castleman disease: potential efficacy and tolerability of a humanized anti-interleukin-6 receptor monoclonal antibody

BACKGROUND: Idiopathic multicentric Castleman disease (iMCD) is a rare polyclonal lymphoproliferative disease caused by the overrepresentation of interleukin-6 (IL-6). Tocilizumab (TCZ) is a humanized monoclonal antibody that binds to the IL-6 receptor and is approved for the treatment of iMCD. The...

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Detalles Bibliográficos
Autores principales: Tomioka, Yasuaki, Otani, Shinji, Tanaka, Shin, Shien, Kazuhiko, Suzawa, Ken, Miyoshi, Kentaroh, Yamamoto, Hiromasa, Okazaki, Mikio, Sugimoto, Seiichiro, Yamane, Masaomi, Toyooka, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448796/
https://www.ncbi.nlm.nih.gov/pubmed/34533616
http://dx.doi.org/10.1186/s40792-021-01297-2