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Structural basis of RNA polymerase inhibition by viral and host factors

RNA polymerase inhibition plays an important role in the regulation of transcription in response to environmental changes and in the virus-host relationship. Here we present the high-resolution structures of two such RNAP-inhibitor complexes that provide the structural bases underlying RNAP inhibiti...

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Detalles Bibliográficos
Autores principales: Pilotto, Simona, Fouqueau, Thomas, Lukoyanova, Natalya, Sheppard, Carol, Lucas-Staat, Soizick, Díaz-Santín, Luis Miguel, Matelska, Dorota, Prangishvili, David, Cheung, Alan C. M., Werner, Finn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448823/
https://www.ncbi.nlm.nih.gov/pubmed/34535646
http://dx.doi.org/10.1038/s41467-021-25666-5