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Structural basis of RNA polymerase inhibition by viral and host factors
RNA polymerase inhibition plays an important role in the regulation of transcription in response to environmental changes and in the virus-host relationship. Here we present the high-resolution structures of two such RNAP-inhibitor complexes that provide the structural bases underlying RNAP inhibiti...
Autores principales: | Pilotto, Simona, Fouqueau, Thomas, Lukoyanova, Natalya, Sheppard, Carol, Lucas-Staat, Soizick, Díaz-Santín, Luis Miguel, Matelska, Dorota, Prangishvili, David, Cheung, Alan C. M., Werner, Finn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448823/ https://www.ncbi.nlm.nih.gov/pubmed/34535646 http://dx.doi.org/10.1038/s41467-021-25666-5 |
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