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Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions

Fibrotic scar tissue limits central nervous system regeneration in adult mammals. The extent of fibrotic tissue generation and distribution of stromal cells across different lesions in the brain and spinal cord has not been systematically investigated in mice and humans. Furthermore, it is unknown w...

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Detalles Bibliográficos
Autores principales: Dias, David O., Kalkitsas, Jannis, Kelahmetoglu, Yildiz, Estrada, Cynthia P., Tatarishvili, Jemal, Holl, Daniel, Jansson, Linda, Banitalebi, Shervin, Amiry-Moghaddam, Mahmood, Ernst, Aurélie, Huttner, Hagen B., Kokaia, Zaal, Lindvall, Olle, Brundin, Lou, Frisén, Jonas, Göritz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448846/
https://www.ncbi.nlm.nih.gov/pubmed/34535655
http://dx.doi.org/10.1038/s41467-021-25585-5