Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence

The specific niche adaptations that facilitate primary disease and Acute Lymphoblastic Leukaemia (ALL) survival after induction chemotherapy remain unclear. Here, we show that Bone Marrow (BM) adipocytes dynamically evolve during ALL pathogenesis and therapy, transitioning from cellular depletion in...

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Detalles Bibliográficos
Autores principales: Heydt, Q., Xintaropoulou, C., Clear, A., Austin, M., Pislariu, I., Miraki-Moud, F., Cutillas, P., Korfi, K., Calaminici, M., Cawthorn, W., Suchacki, K., Nagano, A., Gribben, J. G., Smith, M., Cavenagh, J. D., Oakervee, H., Castleton, A., Taussig, D., Peck, B., Wilczynska, A., McNaughton, L., Bonnet, D., Mardakheh, F., Patel, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448863/
https://www.ncbi.nlm.nih.gov/pubmed/34535653
http://dx.doi.org/10.1038/s41467-021-25540-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448863/
https://www.ncbi.nlm.nih.gov/pubmed/34535653
http://dx.doi.org/10.1038/s41467-021-25540-4

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