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Application of LDH assay for therapeutic efficacy evaluation of ex vivo tumor models

The current standard preclinical oncology models are not able to fully recapitulate therapeutic targets and clinically relevant disease biology, evidenced by the 90% attrition rate of new therapies in clinical trials. Three-dimensional (3D) culture systems have the potential to enhance the relevance...

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Detalles Bibliográficos
Autores principales: Cox, Megan C., Mendes, Rita, Silva, Fernanda, Mendes, Teresa F., Zelaya-Lazo, Adelyn, Halwachs, Kathleen, Purkal, Julie J., Isidro, Inês A., Félix, Ana, Boghaert, Erwin R., Brito, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448883/
https://www.ncbi.nlm.nih.gov/pubmed/34535719
http://dx.doi.org/10.1038/s41598-021-97894-0