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Application of LDH assay for therapeutic efficacy evaluation of ex vivo tumor models
The current standard preclinical oncology models are not able to fully recapitulate therapeutic targets and clinically relevant disease biology, evidenced by the 90% attrition rate of new therapies in clinical trials. Three-dimensional (3D) culture systems have the potential to enhance the relevance...
Autores principales: | Cox, Megan C., Mendes, Rita, Silva, Fernanda, Mendes, Teresa F., Zelaya-Lazo, Adelyn, Halwachs, Kathleen, Purkal, Julie J., Isidro, Inês A., Félix, Ana, Boghaert, Erwin R., Brito, Catarina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448883/ https://www.ncbi.nlm.nih.gov/pubmed/34535719 http://dx.doi.org/10.1038/s41598-021-97894-0 |
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