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An oral cancer vaccine using a Bifidobacterium vector suppresses tumor growth in a syngeneic mouse bladder cancer model

Cancer immunotherapy using immune-checkpoint inhibitors (ICIs) such as PD-1/PD-L1 inhibitors has been well established for various types of cancer. Monotherapy with ICIs, however, can achieve a durable response in only a subset of patients. There is a great unmet need for the ICI-resistant-tumors. S...

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Detalles Bibliográficos
Autores principales: Kitagawa, Koichi, Tatsumi, Maho, Kato, Mako, Komai, Shota, Doi, Hazuki, Hashii, Yoshiko, Katayama, Takane, Fujisawa, Masato, Shirakawa, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449024/
https://www.ncbi.nlm.nih.gov/pubmed/34589578
http://dx.doi.org/10.1016/j.omto.2021.08.009