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A fully reversible 25-hydroxy steroid kinase involved in oxygen-independent cholesterol side-chain oxidation

The degradation of cholesterol and related steroids by microbes follows fundamentally different strategies in aerobic and anaerobic environments. In anaerobic bacteria, the primary C26 of the isoprenoid side chain is hydroxylated without oxygen via a three-step cascade: (i) water-dependent hydroxyla...

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Detalles Bibliográficos
Autores principales: Jacoby, Christian, Goerke, Malina, Bezold, Dominik, Jessen, Henning, Boll, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449060/
https://www.ncbi.nlm.nih.gov/pubmed/34425106
http://dx.doi.org/10.1016/j.jbc.2021.101105