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Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli
Microorganisms can be metabolically engineered to produce specialized plant metabolites. However, these methods are limited by low productivity and intracellular accumulation of metabolites. We sought to use transport engineering for producing reticuline, an important intermediate in the alkaloid bi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449128/ https://www.ncbi.nlm.nih.gov/pubmed/34567974 http://dx.doi.org/10.1016/j.mec.2021.e00184 |