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Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli

Microorganisms can be metabolically engineered to produce specialized plant metabolites. However, these methods are limited by low productivity and intracellular accumulation of metabolites. We sought to use transport engineering for producing reticuline, an important intermediate in the alkaloid bi...

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Detalles Bibliográficos
Autores principales: Yamada, Yasuyuki, Urui, Miya, Oki, Hidehiro, Inoue, Kai, Matsui, Haruyuki, Ikeda, Yoshito, Nakagawa, Akira, Sato, Fumihiko, Minami, Hiromichi, Shitan, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449128/
https://www.ncbi.nlm.nih.gov/pubmed/34567974
http://dx.doi.org/10.1016/j.mec.2021.e00184