A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling

Hypoxia is a critical factor in solid tumors that has been associated with cancer progression and aggressiveness. We recently developed a hypoxia fate mapping system to trace post-hypoxic cells within a tumor for the first time. This approach uses an oxygen-dependent fluorescent switch and allowed u...

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Detalles Bibliográficos
Autores principales: Rocha, Heber L., Godet, Inês, Kurtoglu, Furkan, Metzcar, John, Konstantinopoulos, Kali, Bhoyar, Soumitra, Gilkes, Daniele M., Macklin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449249/
https://www.ncbi.nlm.nih.gov/pubmed/34568781
http://dx.doi.org/10.1016/j.isci.2021.102935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449249/
https://www.ncbi.nlm.nih.gov/pubmed/34568781
http://dx.doi.org/10.1016/j.isci.2021.102935

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