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A persistent invasive phenotype in post-hypoxic tumor cells is revealed by fate mapping and computational modeling
Hypoxia is a critical factor in solid tumors that has been associated with cancer progression and aggressiveness. We recently developed a hypoxia fate mapping system to trace post-hypoxic cells within a tumor for the first time. This approach uses an oxygen-dependent fluorescent switch and allowed u...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449249/ https://www.ncbi.nlm.nih.gov/pubmed/34568781 http://dx.doi.org/10.1016/j.isci.2021.102935 |