Missense mutation of a conserved residue in UNC-112 (kindlin) eliminates binding to PAT-4 (ILK)

C. elegans UNC-112 (kindlin) is required for muscle sarcomere assembly, and is one component of a conserved four-protein complex that associates with the cytoplasmic tail of integrin at the base of integrin adhesion complexes in muscle. The four-protein complex consists of UNC-112 (kindlin), PAT-4 (...

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Detalles Bibliográficos
Autores principales: Qadota, Hiroshi, Oberhauser, Andres F, Benian, Guy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449257/
https://www.ncbi.nlm.nih.gov/pubmed/34549173
http://dx.doi.org/10.17912/micropub.biology.000454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449257/
https://www.ncbi.nlm.nih.gov/pubmed/34549173
http://dx.doi.org/10.17912/micropub.biology.000454

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