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Missense mutation of a conserved residue in UNC-112 (kindlin) eliminates binding to PAT-4 (ILK)
C. elegans UNC-112 (kindlin) is required for muscle sarcomere assembly, and is one component of a conserved four-protein complex that associates with the cytoplasmic tail of integrin at the base of integrin adhesion complexes in muscle. The four-protein complex consists of UNC-112 (kindlin), PAT-4 (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Caltech Library
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449257/ https://www.ncbi.nlm.nih.gov/pubmed/34549173 http://dx.doi.org/10.17912/micropub.biology.000454 |