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Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease
BACKGROUND & AIMS: Polycystic liver disease (PLD) is characterised by increased autophagy and reduced miRNA levels in cholangiocytes. Given that autophagy has been implicated in miRNA regulation, we tested the hypothesis that increased autophagy accounts for miRNA reduction in PLD cholangiocytes...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449272/ https://www.ncbi.nlm.nih.gov/pubmed/34568801 http://dx.doi.org/10.1016/j.jhepr.2021.100345 |