Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease

BACKGROUND & AIMS: Polycystic liver disease (PLD) is characterised by increased autophagy and reduced miRNA levels in cholangiocytes. Given that autophagy has been implicated in miRNA regulation, we tested the hypothesis that increased autophagy accounts for miRNA reduction in PLD cholangiocytes...

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Detalles Bibliográficos
Autores principales: Masyuk, Tatyana, Masyuk, Anatoliy, Trussoni, Christy, Howard, Brynn, Ding, Jingyi, Huang, Bing, LaRusso, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449272/
https://www.ncbi.nlm.nih.gov/pubmed/34568801
http://dx.doi.org/10.1016/j.jhepr.2021.100345

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