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Commonly used anti–von Willebrand factor antibody for multimer analysis cross‐reacts with fibronectin, which is difficult to distinguish from von Willebrand factor

Von Willebrand factor (VWF) is a 500‐ to 15 000‐kDa multimeric protein circulating in the blood. When VWF has a higher molecular weight, its hemostatic activity is greater. The size distribution of VWF multimers is usually analyzed by SDS‐agarose gel electrophoresis followed by immunoblotting. We fo...

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Detalles Bibliográficos
Autores principales: Eura, Yuka, Kokame, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449288/
https://www.ncbi.nlm.nih.gov/pubmed/34568727
http://dx.doi.org/10.1002/rth2.12598