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Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1
COVID-19, caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has presented a serious risk to global public health. The viral main protease M(pro) (also called 3Cl(pro)) encoded by NSP5 is an enzyme essential for viral replication. However, very few host proteins have been experimentally...
Autores principales: | Zhang, Shilei, Wang, Jingfeng, Cheng, Genhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449311/ https://www.ncbi.nlm.nih.gov/pubmed/34452991 http://dx.doi.org/10.1073/pnas.2107108118 |
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