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FGF-2–dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis

Aged skeletal muscle is markedly affected by fatty muscle infiltration, and strategies to reduce the occurrence of intramuscular adipocytes are urgently needed. Here, we show that fibroblast growth factor-2 (FGF-2) not only stimulates muscle growth but also promotes intramuscular adipogenesis. Using...

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Detalles Bibliográficos
Autores principales: Mathes, Sebastian, Fahrner, Alexandra, Ghoshdastider, Umesh, Rüdiger, Hannes A., Leunig, Michael, Wolfrum, Christian, Krützfeldt, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449320/
https://www.ncbi.nlm.nih.gov/pubmed/34493647
http://dx.doi.org/10.1073/pnas.2021013118