Cargando…

MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells

Multiple placental pathologies are associated with failures in trophoblast differentiation, yet the underlying transcriptional regulation is poorly understood. Here, we discovered msh homeobox 2 (MSX2) as a key transcriptional regulator of trophoblast identity using the human trophoblast stem cell m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hornbachner, Ruth, Lackner, Andreas, Papuchova, Henrieta, Haider, Sandra, Knöfler, Martin, Mechtler, Karl, Latos, Paulina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449346/
https://www.ncbi.nlm.nih.gov/pubmed/34507999
http://dx.doi.org/10.1073/pnas.2105130118