Intrinsic physicochemical profile of marketed antibody-based biotherapeutics

Feeding biopharma pipelines with biotherapeutic candidates that possess desirable developability profiles can help improve the productivity of biologic drug discovery and development. Here, we have derived an in silico profile by analyzing computed physicochemical descriptors for the variable region...

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Detalles Bibliográficos
Autores principales: Ahmed, Lucky, Gupta, Priyanka, Martin, Kyle P., Scheer, Justin M., Nixon, Andrew E., Kumar, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449350/
https://www.ncbi.nlm.nih.gov/pubmed/34504010
http://dx.doi.org/10.1073/pnas.2020577118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449350/
https://www.ncbi.nlm.nih.gov/pubmed/34504010
http://dx.doi.org/10.1073/pnas.2020577118

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