Profound Treg perturbations correlate with COVID-19 severity

The hallmark of severe COVID-19 is an uncontrolled inflammatory response, resulting from poorly understood immunological dysfunction. We hypothesized that perturbations in FoxP3(+) T regulatory cells (Treg), key enforcers of immune homeostasis, contribute to COVID-19 pathology. Cytometric and transc...

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Detalles Bibliográficos
Autores principales: Galván-Peña, Silvia, Leon, Juliette, Chowdhary, Kaitavjeet, Michelson, Daniel A., Vijaykumar, Brinda, Yang, Liang, Magnuson, Angela M., Chen, Felicia, Manickas-Hill, Zachary, Piechocka-Trocha, Alicja, Worrall, Daniel P., Hall, Kathryn E., Ghebremichael, Musie, Walker, Bruce D., Li, Jonathan Z., Yu, Xu G., Mathis, Diane, Benoist, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449354/
https://www.ncbi.nlm.nih.gov/pubmed/34433692
http://dx.doi.org/10.1073/pnas.2111315118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449354/
https://www.ncbi.nlm.nih.gov/pubmed/34433692
http://dx.doi.org/10.1073/pnas.2111315118

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