Sequential in vivo labeling of insulin secretory granule pools in INS-SNAP transgenic pigs

β cells produce, store, and secrete insulin upon elevated blood glucose levels. Insulin secretion is a highly regulated process. The probability for insulin secretory granules to undergo fusion with the plasma membrane or being degraded is correlated with their age. However, the molecular features a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kemter, Elisabeth, Müller, Andreas, Neukam, Martin, Ivanova, Anna, Klymiuk, Nikolai, Renner, Simone, Yang, Kaiyuan, Broichhagen, Johannes, Kurome, Mayuko, Zakhartchenko, Valeri, Kessler, Barbara, Knoch, Klaus-Peter, Bickle, Marc, Ludwig, Barbara, Johnsson, Kai, Lickert, Heiko, Kurth, Thomas, Wolf, Eckhard, Solimena, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449372/
https://www.ncbi.nlm.nih.gov/pubmed/34508004
http://dx.doi.org/10.1073/pnas.2107665118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449372/
https://www.ncbi.nlm.nih.gov/pubmed/34508004
http://dx.doi.org/10.1073/pnas.2107665118

Ejemplares similares