5′-Cap sequestration is an essential determinant of HIV-1 genome packaging

HIV-1 selectively packages two copies of its 5′-capped RNA genome (gRNA) during virus assembly, a process mediated by the nucleocapsid (NC) domain of the viral Gag polyprotein and encapsidation signals located within the dimeric 5′ leader of the viral RNA. Although residues within the leader that pr...

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Detalles Bibliográficos
Autores principales: Ding, Pengfei, Kharytonchyk, Siarhei, Kuo, Nansen, Cannistraci, Emily, Flores, Hana, Chaudhary, Ridhi, Sarkar, Mitali, Dong, Xinmei, Telesnitsky, Alice, Summers, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449379/
https://www.ncbi.nlm.nih.gov/pubmed/34493679
http://dx.doi.org/10.1073/pnas.2112475118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449379/
https://www.ncbi.nlm.nih.gov/pubmed/34493679
http://dx.doi.org/10.1073/pnas.2112475118

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