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Diphthamide promotes TOR signaling by increasing the translation of proteins in the TORC1 pathway
Diphthamide, a modification found only on translation elongation factor 2 (EF2), was proposed to suppress −1 frameshifting in translation. Although diphthamide is conserved among all eukaryotes, exactly what proteins are affected by diphthamide deletion is not clear in cells. Through genome-wide pro...
Autores principales: | Zhang, Yugang, Lin, Zhewang, Zhu, Julia, Wang, Miao, Lin, Hening |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449394/ https://www.ncbi.nlm.nih.gov/pubmed/34507998 http://dx.doi.org/10.1073/pnas.2104577118 |
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