Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself

Adaptive immune recognition is mediated by the binding of peptide–human leukocyte antigen complexes by T cells. Positive selection of T cells in the thymus is a fundamental step in the generation of a responding T cell repertoire: only those T cells survive that recognize human peptides presented on...

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Detalles Bibliográficos
Autores principales: Koncz, Balázs, Balogh, Gergő M., Papp, Benjamin T., Asztalos, Leó, Kemény, Lajos, Manczinger, Máté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449404/
https://www.ncbi.nlm.nih.gov/pubmed/34507984
http://dx.doi.org/10.1073/pnas.2100542118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449404/
https://www.ncbi.nlm.nih.gov/pubmed/34507984
http://dx.doi.org/10.1073/pnas.2100542118

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