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Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering

Pentameric ligand-gated ion channels undergo subtle conformational cycling to control electrochemical signal transduction in many kingdoms of life. Several crystal structures have now been reported in this family, but the functional relevance of such models remains unclear. Here, we used small-angle...

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Detalles Bibliográficos
Autores principales: Lycksell, Marie, Rovšnik, Urška, Bergh, Cathrine, Johansen, Nicolai T., Martel, Anne, Porcar, Lionel, Arleth, Lise, Howard, Rebecca J., Lindahl, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449418/
https://www.ncbi.nlm.nih.gov/pubmed/34504004
http://dx.doi.org/10.1073/pnas.2108006118