Circ_PIP5K1A regulates cisplatin resistance and malignant progression in non-small cell lung cancer cells and xenograft murine model via depending on miR-493-5p/ROCK1 axis

BACKGROUND: Chemoresistance limits the therapeutic effect of cisplatin (DDP) on non-small cell lung cancer (NSCLC). Circular RNAs (circRNAs) function as important regulators in chemoresistance. This study aimed to explore the regulation of circRNA Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alp...

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Detalles Bibliográficos
Autores principales: Feng, Nan, Guo, Zhi, Wu, Xiaokang, Tian, Ying, Li, Yue, Geng, Yan, Yu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449484/
https://www.ncbi.nlm.nih.gov/pubmed/34537072
http://dx.doi.org/10.1186/s12931-021-01840-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449484/
https://www.ncbi.nlm.nih.gov/pubmed/34537072
http://dx.doi.org/10.1186/s12931-021-01840-7

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