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Circ_PIP5K1A regulates cisplatin resistance and malignant progression in non-small cell lung cancer cells and xenograft murine model via depending on miR-493-5p/ROCK1 axis

BACKGROUND: Chemoresistance limits the therapeutic effect of cisplatin (DDP) on non-small cell lung cancer (NSCLC). Circular RNAs (circRNAs) function as important regulators in chemoresistance. This study aimed to explore the regulation of circRNA Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alp...

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Detalles Bibliográficos
Autores principales:	Feng, Nan, Guo, Zhi, Wu, Xiaokang, Tian, Ying, Li, Yue, Geng, Yan, Yu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449484/ https://www.ncbi.nlm.nih.gov/pubmed/34537072 http://dx.doi.org/10.1186/s12931-021-01840-7

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