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HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA

BACKGROUND: Certain risk alleles associated with autoantibody-positive rheumatoid arthritis (RA) have been linked to poorer prognoses. In patients with autoantibody-positive RA, abatacept shows differential efficacy to tumor necrosis factor inhibitors. Our aim was to investigate the relationship bet...

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Detalles Bibliográficos
Autores principales: Rigby, William, Buckner, Jane H., Louis Bridges, S., Nys, Marleen, Gao, Sheng, Polinsky, Martin, Ray, Neelanjana, Bykerk, Vivian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449494/
https://www.ncbi.nlm.nih.gov/pubmed/34537057
http://dx.doi.org/10.1186/s13075-021-02607-7