Modeling and Simulation for Individualized Therapy of Amisulpride in Chinese Patients with Schizophrenia: Focus on Interindividual Variability, Therapeutic Reference Range and the Laboratory Alert Level

PURPOSE: To explain the high inter-individual variability (IIV) and the frequency of exceeding the therapeutic reference range and the laboratory alert level of amisulpride, a population pharmacokinetic (PPK) model in Chinese patients with schizophrenia was built based on therapeutic drug monitoring...

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Detalles Bibliográficos
Autores principales: Huang, Shanqing, Li, Lu, Wang, Zhanzhang, Xiao, Tao, Li, Xiaolin, Liu, Shujing, Zhang, Ming, Lu, Haoyang, Wen, Yuguan, Shang, Dewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449641/
https://www.ncbi.nlm.nih.gov/pubmed/34548782
http://dx.doi.org/10.2147/DDDT.S327506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449641/
https://www.ncbi.nlm.nih.gov/pubmed/34548782
http://dx.doi.org/10.2147/DDDT.S327506

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