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Engineering a probiotic strain of Escherichia coli to induce the regression of colorectal cancer through production of 5‐aminolevulinic acid

Bacterial vectors can be engineered to generate microscopic living therapeutics to produce and deliver anticancer agents. Escherichia coli Nissle 1917 (Nissle 1917) is a promising candidate with probiotic properties. Here, we used Nissle 1917 to develop a metabolic strategy to produce 5‐aminolevulin...

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Detalles Bibliográficos
Autores principales: Chen, Junhao, Li, Xiaohong, Liu, Yumei, Su, Tianyuan, Lin, Changsen, Shao, Lijun, Li, Lanhua, Li, Wanwei, Niu, Guoyu, Yu, Jing, Liu, Ling, Li, Miaomiao, Yu, Xiaoli, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449674/
https://www.ncbi.nlm.nih.gov/pubmed/34272828
http://dx.doi.org/10.1111/1751-7915.13894