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Loss of GATA4 C-Terminus by p.S335X Mutation Modulates Coronary Artery Vascular Smooth Muscle Cell Phenotype

Coronary artery disease (CAD) has been the leading cause of morbidity and mortality worldwide, and its pathogenesis is closely related with the proliferation and migration of vascular smooth muscle cell (VSMC). We previously reported a truncated GATA4 protein lacking C-terminus induced by p.S335X mu...

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Detalles Bibliográficos
Autores principales: Yu, Ting-Yan, Chen, Xin-Xin, Liu, Qing-Wen, Ma, Fang-Fang, Huang, Hong-Lang, Zhou, Lei, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449727/
https://www.ncbi.nlm.nih.gov/pubmed/34545275
http://dx.doi.org/10.1155/2021/3698386