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A New Intraepithelial γδ T-Lymphocyte Marker for Celiac Disease Classification in Formalin-Fixed Paraffin-Embedded (FFPE) Duodenal Biopsies

BACKGROUND: The histopathologic diagnosis of celiac disease (CD) may be challenging when the duodenal biopsies mucosal injury is limited. Intraepithelial T-lymphocytes (IELs) can be useful to characterize the degree of mucosal inflammation. A small fraction of IELs expresses the γδ T-cell receptor (...

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Detalles Bibliográficos
Autores principales: Popp, Alina, Taavela, Juha, Graziano, Paolo, Parente, Paola, Covelli, Claudia, Lamacchia, Carmela, Andriulli, Angelo, Mäki, Markku, Isola, Jorma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449760/
https://www.ncbi.nlm.nih.gov/pubmed/33140183
http://dx.doi.org/10.1007/s10620-020-06680-x