Casein Kinase-1-Alpha Inhibitor (D4476) Sensitizes Microsatellite Instable Colorectal Cancer Cells to 5-Fluorouracil via Authophagy Flux Inhibition

Adjuvant chemotherapy with 5-fluorouracil (5-FU) does not improve survival of patients suffering from a form of colorectal cancer (CRC) characterized by high level of microsatellite instability (MSI-H). Given the importance of autophagy and multi-drug-resistant (MDR) proteins in chemotherapy resista...

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Detalles Bibliográficos
Autores principales: Siri, Morvarid, Behrouj, Hamid, Dastghaib, Sanaz, Zamani, Mozhdeh, Likus, Wirginia, Rezaie, Sedigheh, Hudecki, Jacek, Khazayel, Saeed, Łos, Marek J., Mokarram, Pooneh, Ghavami, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449776/
https://www.ncbi.nlm.nih.gov/pubmed/34536148
http://dx.doi.org/10.1007/s00005-021-00629-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449776/
https://www.ncbi.nlm.nih.gov/pubmed/34536148
http://dx.doi.org/10.1007/s00005-021-00629-2

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