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Casein Kinase-1-Alpha Inhibitor (D4476) Sensitizes Microsatellite Instable Colorectal Cancer Cells to 5-Fluorouracil via Authophagy Flux Inhibition

Adjuvant chemotherapy with 5-fluorouracil (5-FU) does not improve survival of patients suffering from a form of colorectal cancer (CRC) characterized by high level of microsatellite instability (MSI-H). Given the importance of autophagy and multi-drug-resistant (MDR) proteins in chemotherapy resista...

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Detalles Bibliográficos
Autores principales:	Siri, Morvarid, Behrouj, Hamid, Dastghaib, Sanaz, Zamani, Mozhdeh, Likus, Wirginia, Rezaie, Sedigheh, Hudecki, Jacek, Khazayel, Saeed, Łos, Marek J., Mokarram, Pooneh, Ghavami, Saeid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449776/ https://www.ncbi.nlm.nih.gov/pubmed/34536148 http://dx.doi.org/10.1007/s00005-021-00629-2

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