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Empirical versus theoretical power and type I error (false-positive) rates estimated from real murine aging research data
We assess the degree of phenotypic variation in a cohort of 24-month-old male C57BL/6 mice. Because murine studies often use small sample sizes, if the commonly relied upon assumption of a normal distribution of residuals is not met, it may inflate type I error rates. In this study, 3–20 mice are re...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449850/ https://www.ncbi.nlm.nih.gov/pubmed/34407413 http://dx.doi.org/10.1016/j.celrep.2021.109560 |