Empirical versus theoretical power and type I error (false-positive) rates estimated from real murine aging research data

We assess the degree of phenotypic variation in a cohort of 24-month-old male C57BL/6 mice. Because murine studies often use small sample sizes, if the commonly relied upon assumption of a normal distribution of residuals is not met, it may inflate type I error rates. In this study, 3–20 mice are re...

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Detalles Bibliográficos
Autores principales: Alfaras, Irene, Ejima, Keisuke, Teixeira, Camila Vieira Ligo, Di Germanio, Clara, Mitchell, Sarah J., Hamilton, Samuel, Ferrucci, Luigi, Price, Nathan L., Allison, David B., Bernier, Michel, de Cabo, Rafael
Formato: Online Artigo Texto
Idioma:English
Publicado: 2021
Materias:
Article
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449850/
https://www.ncbi.nlm.nih.gov/pubmed/34407413
http://dx.doi.org/10.1016/j.celrep.2021.109560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449850/
https://www.ncbi.nlm.nih.gov/pubmed/34407413
http://dx.doi.org/10.1016/j.celrep.2021.109560

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