High-fat diet increases gliosis and immediate early gene expression in APOE3 mice, but not APOE4 mice

BACKGROUND: APOE4 is the strongest genetic risk factor for Alzheimer’s disease (AD), and obesity is a strong environmental risk factor for AD. These factors result in multiple central nervous system (CNS) disturbances and significantly increase chances of AD. Since over 20% of the US population carr...

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Detalles Bibliográficos
Autores principales: Jones, Nahdia S., Watson, Katarina Q., Rebeck, G. William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449905/
https://www.ncbi.nlm.nih.gov/pubmed/34537055
http://dx.doi.org/10.1186/s12974-021-02256-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449905/
https://www.ncbi.nlm.nih.gov/pubmed/34537055
http://dx.doi.org/10.1186/s12974-021-02256-2

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