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High-fat diet increases gliosis and immediate early gene expression in APOE3 mice, but not APOE4 mice

BACKGROUND: APOE4 is the strongest genetic risk factor for Alzheimer’s disease (AD), and obesity is a strong environmental risk factor for AD. These factors result in multiple central nervous system (CNS) disturbances and significantly increase chances of AD. Since over 20% of the US population carr...

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Detalles Bibliográficos
Autores principales:	Jones, Nahdia S., Watson, Katarina Q., Rebeck, G. William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449905/ https://www.ncbi.nlm.nih.gov/pubmed/34537055 http://dx.doi.org/10.1186/s12974-021-02256-2

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