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Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue

Hyperglycemia affects over 400 million individuals worldwide. The detrimental health effects are well studied at the tissue level, but the in vivo effects at the organelle level are poorly understood. To establish such an in vivo model, we used mice lacking TXNIP, a negative regulator of glucose upt...

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Detalles Bibliográficos
Autores principales: Waldhart, Althea N., Muhire, Brejnev, Johnson, Ben, Pettinga, Dean, Madaj, Zachary B., Wolfrum, Emily, Dykstra, Holly, Wegert, Vanessa, Pospisilik, J. Andrew, Han, Xianlin, Wu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449951/
https://www.ncbi.nlm.nih.gov/pubmed/34348139
http://dx.doi.org/10.1016/j.celrep.2021.109488