Cargando…
Excess dietary carbohydrate affects mitochondrial integrity as observed in brown adipose tissue
Hyperglycemia affects over 400 million individuals worldwide. The detrimental health effects are well studied at the tissue level, but the in vivo effects at the organelle level are poorly understood. To establish such an in vivo model, we used mice lacking TXNIP, a negative regulator of glucose upt...
Autores principales: | Waldhart, Althea N., Muhire, Brejnev, Johnson, Ben, Pettinga, Dean, Madaj, Zachary B., Wolfrum, Emily, Dykstra, Holly, Wegert, Vanessa, Pospisilik, J. Andrew, Han, Xianlin, Wu, Ning |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449951/ https://www.ncbi.nlm.nih.gov/pubmed/34348139 http://dx.doi.org/10.1016/j.celrep.2021.109488 |
Ejemplares similares
-
PPARγ and C/EBPα response to acute cold stress in brown adipose tissue
por: Lau, Kin H., et al.
Publicado: (2022) -
Differential effects of sugar and fat on adipose tissue inflammation
por: Avequin, Tracey, et al.
Publicado: (2023) -
Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP
por: Waldhart, Althea N., et al.
Publicado: (2023) -
Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-‘omics analysis of the liver metabolic response to viral infection
por: Madaj, Zachary B, et al.
Publicado: (2023) -
Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism
por: Scheele, Camilla, et al.
Publicado: (2019)