Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity

BACKGROUND: Tumor-associated macrophages (TAMs) play a key immunosuppressive role that limits the ability of the immune system to fight cancer and hinder the antitumoral efficacy of most treatments currently applied in the clinic. Previous studies have evaluated the antitumoral immune response trigg...

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Detalles Bibliográficos
Autores principales: Anfray, Clément, Mainini, Francesco, Digifico, Elisabeth, Maeda, Akihiro, Sironi, Marina, Erreni, Marco, Anselmo, Achille, Ummarino, Aldo, Gandoy, Sara, Expósito, Francisco, Redrado, Miriam, Serrano, Diego, Calvo, Alfonso, Martens, Marvin, Bravo, Susana, Mantovani, Alberto, Allavena, Paola, Andón, Fernando Torres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449972/
https://www.ncbi.nlm.nih.gov/pubmed/34531246
http://dx.doi.org/10.1136/jitc-2021-002408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449972/
https://www.ncbi.nlm.nih.gov/pubmed/34531246
http://dx.doi.org/10.1136/jitc-2021-002408

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